1. Borax was used for treatment of 31 patients suffering from skeletal fluorosis

2. And more than 10 million are afflicted by fluorosis, which can soften and disfigure teeth and bones.

3. Also, the 200 μg/kg bw per day effect level is within the range of daily intakes predicted (i.e., based on modelling) to result in bone fluoride concentrations associated with adverse skeletal effects in humans.4 An Advisory Review Panel of dental researchers recently reviewed the available data on the relationship between daily fluoride intake in childhood and the occurrence of dental fluorosis.